Parkinson's Disease

Description

Parkinson's disease is a progressive, degenerative neurological condition that affects the control of body movements. It causes trembling in the hands, arms, legs, jaw, and face; rigidity or stiffness of the limbs or trunk; slowness of body movements; and unstable posture and difficulty in walking. Early symptoms are subtle and occur gradually.

It happens when the neurons (nerve cells) that normally produce dopamine in the brain gradually die. The death of these cells leads to abnormally low levels of dopamine, a chemical which helps relay messages between areas of the brain that control body movement. Low levels of dopamine give rise to difficulty in controlling muscle tension and muscle movement, both at rest and during periods of activity.

Parkinson's disease currently affects about 40,000 Australians. Approximately one to two people per 1,000 are estimated to have the disorder, with the incidence increasing to one in 100 of people over the age of 60. It is slightly more common in men than in women.

So far, scientists have not determined the reason why some people develop Parkinson's disease and others do not. Suggested causes include environmental factors such as pesticides, toxins and chemicals; genetic factors (although the disease appears to be inherited in only a small percentage of cases) and head trauma.

Treatment

A variety of medications enable the disease to be managed and provide dramatic relief from the symptoms. In some cases, surgery is an appropriate treatment. Some doctors recommend multi-disciplinary treatment by physiotherapists, dietitians and counsellors. No two people will experience the condition in the same way, so management will vary.

Prognosis

Parkinson's disease is a chronic, progressive illness, and no drug can prevent the progression of the disease.

Further Information and Support

Support

# Parkinson’s NSW Inc, 25 Kharthoum Road, North Ryde NSW 2133 - Ph: (02) 8875 8900 or InfoLine Freecall 1800 644 189 or email pnsw@parkinsonsnsw.org.au 
# Parkinson’s Victoria, 20 Kingston Road, Cheltenham Vic - Ph (03) 9551 1122
# Parkinson's Queensland, PO Box 1684, Springwood QLD 4127 Ph:(07) 3209 1588
# Parkinson's SA, 23A King William Road, Unley, SA 5061 - Ph (08)8357 8909
# Parkinson's WA, Centre for Neurological Support, The Niche - Suite B,  11 Aberdare Road, NEDLANDS  WA  6009. Ph: (08) 9346 7373
# Parkinson's ACT, PO Box 717, Mawson ACT 2607 - Ph: (02) 6290 1984
# Parkinson's Tasmania, 17 St Helen Street, Lindisfarne TAS 7015 - Ph: (03) 6243 6510

Information

# Australian Commonwealth Department of Health and Ageing  www.healthinsite.gov.au
# National Institutes of Health USA  www.ninds.nih.gov/health_and_medical/disorders/parkinsons_disease.htm
# Harvard Medical School www.intelihealth.com  (/Look It Up – Health A-Z
# Michael J Fox Foundation www.michaeljfox.org
# Parkinson Foundation USA www.parkinsonfoundation.org
# Worldwide Education & Awareness for Movement Disorders (WE MOVE) www.wemove.org

Reviewed by Professor John Morris, Neurologist, Westmead Hospital